[user104658]

Originally Posted by LeatherTrumpet

The British Chambers of Commerce has estimated that the annual cost to the UK of EU regulation is £7.4 billion squid.

If the benefit of being in the single market exceeds £7.4 billion (spoiler: it does) then this figure is utterly irrelevant. Any benefit of leaving is based on the flimsy assumption that we will be able to secure lucrative trade deals that will equal the single market in terms of economic benefit (spoiler: we won't).