[Cherie]

Controversy over the number of doses in the Pfizer vials



https://www.rte.ie/news/coronavirus/...-pfizer-doses/

How many doses?

Until recently, each vial of the BioNTech-Pfizer vaccine was considered to officially contain five doses.

After being thawed, the contents of each vial are diluted with 1.8ml of saline solution, creating a total of 2.25ml of injectable solution. With each dose 0.3ml, in theory there are just over seven doses.

But theory and practice are different. Medical personnel are unable to measure so precisely the doses to get seven doses they can inject into people.

But the found they could - with the right equipment - reliably get six doses out of the vials.

Both EU and US regulators now consider that the vials contain six doses and have authorised the use of the sixth dose.

However the European Medicines Agency noted that this sixth dose depends on the availability of specific syringes.

[AnnieK]

Originally Posted by MTVN

Great news Annie

My 93 year old Grandma has had her first jab this morning too. She lives in the Isle of Man so it's been a bit slower to get to her but they're pretty much Covid free there anyway. They've transformed the airport into a vaccination centre and she was adament she would drive there and back herself but has eventually relented and let my cousin drive her in case her arm was sore afterwards or anything, just as well because she's an awful driver at the best of times

Great news she's vaccinated.

[Cherie]

Britain raced ahead in the battle to secure vaccine supplies by announcing bulk manufacturing of up to 60 million doses of a new jab.
A vaccine created by French firm Valneva will start large-scale production at a plant in Livingston, Scotland.
If the Valneva jab gets full authorisation it will mean the UK has hopes for an astonishing 200 million jabs, more than enough for all its citizens to get both doses required with some left over.
It is an “inactivated whole virus” vaccine, using particles that stimulate an antibody response.
Health Secretary Matt Hancock tweeted: “The Valneva vaccine will be another vital tool in our fight against the virus if approved.” He said the Scottish production was “another fantastic example of the strength of our Union”.
Under the national plan for vaccinations, the UK has portfolio of 100 million Oxford/AstraZeneca doses, 40 million of the Pfizer jab, and 17 million of the Moderna vaccine, in addition to 60 million planned from Valneva.

However, the European Union last night stepped up its demands to be given some of the UK-manufactured Oxford/AstraZeneca batches after plants in Europe failed to produce adequate yields to fulfil its contracts with the company.
Boris Johnson will use a visit to Scotland later today to argue that the Union has been integral in administering the coronavirus vaccine, providing Covid testing and giving economic support north of the border during the pandemic.
The Prime Minister spoke about the "great benefits of co-operation" to beat the coronavirus crisis, which has claimed more than 100,000 lives in the UK.
The visit comes as calls grow for a second independence vote for Scotland.
First Minister Nicola Sturgeon said Mr Johnson's visit to Scotland is "not essential" during the current lockdown.

https://www.standard.co.uk/news/uk/u...a-b906243.html

[bots]

The EU are angry because the UK have shown we can set up a better vaccine deal, faster now that they are out of the EU. It's about the only thing we have done better

[Cherie]

Originally Posted by bitontheslide

The EU are angry because the UK have shown we can set up a better vaccine deal, faster now that they are out of the EU. It's about the only thing we have done better

I think they also have a problem in that Italy, Germany, France and Spain wanted to use emergency powers to approve vaccines but were talked down by Brussels who wanted the bloc to move together

[arista]

[arista]

[Denver]

Originally Posted by bitontheslide

The EU are angry because the UK have shown we can set up a better vaccine deal, faster now that they are out of the EU. It's about the only thing we have done better

It shows their true colours threatening to block exports of vaccines already paid for because they are clueless

[Nicky91]

Originally Posted by Denver

It shows their true colours threatening to block exports of vaccines already paid for because they are clueless

we cannot vaccinate right now all because of you guys

[Denver]

Originally Posted by Nicky91

we cannot vaccinate right now all because of you guys

No blame yourself we brought a large number of doses so they are legally not allowed to stop that plus wasn't France against buying a large number number of vaccines because they wanted to use their own? Then throw a paddy when theirs was postponed by a year

[Nicky91]

also AstraZeneca isn't very effective compared to the other vaccines anyway

[Denver]

They will try to block it but still expect us to give them the Oxford ones

[Cherie]

Originally Posted by Nicky91

we cannot vaccinate right now all because of you guys

AZ has not been approved by the EMA so if you cannot vaccinate with AZ so any lack of vaccination must currently be due to Pfizer issues which is the vaccine the EU has approved?

[arista]

[Cherie]

Originally Posted by arista

that picture and headline

[Zizu]

FFS

Vaccine BAN: Germany to stop giving AstraZeneca jab to over-65s in bombshell move.

Germany's vaccine committee made the announcement this afternoon, and said the AstraZeneca vaccine should only be given to people aged under 65. The update to its vaccine recommendation is due to lack of sufficient data to recommend use in older age groups, it said.

"The AstraZeneca vaccine, unlike the mRNA vaccines, should only be offered to people aged 18-64 years at each stage."

https://www.express.co.uk/news/world...ne-covid19/amp


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[MTVN]

Feels like we're building a very precarious house of cards right now

Imagine if all these vaccinations in the last month were basically for nothing

[Cherie]

Originally Posted by Zizu

FFS

Vaccine BAN: Germany to stop giving AstraZeneca jab to over-65s in bombshell move.

Germany's vaccine committee made the announcement this afternoon, and said the AstraZeneca vaccine should only be given to people aged under 65. The update to its vaccine recommendation is due to lack of sufficient data to recommend use in older age groups, it said.

"The AstraZeneca vaccine, unlike the mRNA vaccines, should only be offered to people aged 18-64 years at each stage."

https://www.express.co.uk/news/world...ne-covid19/amp


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Which kinda puts them at odds with Brussels demanding vaccines now when they are vaccinating the older cohort

[AnnieK]

Sounds a bit salty to me.....in the middle of the EU trying to flex their muscles for a vaccine they haven't approved and now are casting doubt over the efficacy

[arista]

The EU have to come to our Courts on the Stand.

An expert said.

[Cherie]

Originally Posted by AnnieK

Sounds a bit salty to me.....in the middle of the EU trying to flex their muscles for a vaccine they haven't approved and now are casting doubt over the efficacy

It does seem very convenient, and if the EMA have the final approval why is Germany jumping the gun...all very odd and feels political

[Cherie]

EMA expected to approve AZ for use in all ages tomorrow

Germany have secured their own supply of German based Pfizer

[Zizu]

Originally Posted by Cherie

EMA expected to approve AZ for use in all ages tomorrow

Yes that is what I heard earlier... although Germany will stand by their decision to only give AstraZenica to their UNDER 65s ..


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[MTVN]

UK phase three trials of the experimental Novavax COVID-19 vaccine have found it demonstrated 89.3% efficacy against the virus.

Preliminary analysis showed the new UK variant was detected in more than half of the coronavirus cases recorded in the trials, with the vaccine candidate shown to be 95.6% effective against the original strain and 85.6% effective against the variant.

Prime Minister Boris Johnson said the Medicines and Healthcare products Regulatory Agency will start to assess the vaccination straight away.

The study involved more than 15,000 participants aged 18 to 84, with 27% aged over 65.

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An early stage study carried out on 4,400 people in South Africa has shown that the Novavax treatment has "significant clinical efficacy" against the South African variant of the virus.

The UK has already ordered 60 million vials of the vaccine which will be manufactured at the Fujifilm plant in Stockton-on-Tees.

https://news.sky.com/story/covid-19-...ctive-12201756

[arista]